Animal Genomics and Bioresource Research Unit

The laboratory of animal cytogenetics and comparative genomics (ACCG) was established in 2009 to promote expertise in chromosome analysis, comparative genomics, and genetic diversity in animals. Our aim is to clarify genome and chromosome structures to better comprehend genetic diversity and evolutionary processes using both cytogenetic, molecular biology, and genomic techniques. Karyotype and genomic evolution identify the processes of evolutionary changes in vertebrates, and chromosome homologies between different species are deduced by comparative chromosome mapping using cDNA or BACs. These techniques are now assessed through global research collaboration to conduct cross-species chromosome mapping for map-poor species, define intra- and inter-chromosomal rearrangements, and indicate sex chromosome evolution. Organization of repetitive elements in vertebrate genomes involves isolating satellite DNAs that may act as substrates for homologous or non-homologous recombination in genome rearrangements. An effective approach using fosmid library is ongoing to discover stDNAs from an increasing number of lineages. Single-nucleotide polymorphism (SNP), microsatellite, and mitochondrial DNA are used to clarify evolutionary steps and diversity in vertebrates and address the status of genetic relationships and identification in terms of phylogenetics and barcodes. The lab housing KURDI-funded Kasetsart University Research and Development Institute, Center of Excellence on Agricultural Biotechnology: (AG-BIO/PERDO-CHE), the Center for Advanced Studies in Tropical Natural Resources, National Research University-Kasetsart University (CASTNAR, NRU-KU), the National Research Council of Thailand (NRCT), the Conservation Research and Education Division, Zoological Park Organization of Thailand, Thailand Research Fund (TRF), National Science and Technology Development Agency (NSTDA), and National Primate Research Center, Chulalongkorn University, Thailand provides cytogenetic resources and training for the scientific community in cytogenetics, genomics, and diversity. Our research goals are driven by the need to ensure an efficient and sustainable supply of medicine, food, and natural resources by addressing this major global challenge.